Method Development
Creating the Technologies That Don’t Exist Yet
Some research questions are so innovative, so ahead of their time, that no standard protocol can answer them. At AUGenomics, we thrive on this challenge. Our method development services are built for scientists who are pushing the boundaries of biology—those working on creative, transformative technologies that demand new solutions.
When off-the-shelf kits and conventional workflows fall short, AUGenomics collaborates with you to design, optimize, and validate completely new approaches. Whether you need to adapt an existing method, develop a novel sequencing assay, or integrate multiple technologies into a hybrid workflow, our team has the expertise and flexibility to bring your bold ideas to life.
What Our Method Development Services Entail
Method development is more than troubleshooting or protocol tweaking—it’s scientific innovation in action. This service empowers researchers to:
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Create custom sequencing workflows for unique samples, rare modifications, or emerging omics technologies.
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Optimize experimental pipelines to overcome technical barriers and improve sensitivity, specificity, or efficiency.
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Validate novel approaches that open new possibilities for discovery.
AUGenomics brings together NGS expertise, molecular biology innovation, and collaborative problem-solving to develop methods that go beyond the limits of current technologies.
Key Advantages of AUGenomics Method Development
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Innovation-Driven: Designed specifically for novel research questions and disruptive technologies.
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Collaborative Partnership: We work side-by-side with your team, sharing ideas and insights at every stage.
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Custom-Built Solutions: No reliance on cookie-cutter workflows—every method is tailored to your needs.
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Multi-Technology Expertise: Combines genomics, transcriptomics, epigenetics, and multi-omic strategies.
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Support for Rare Targets: Specialized protocols for low-abundance molecules, rare modifications, or unconventional sample types.
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Rapid Iteration: Agile development cycles allow testing, refinement, and scaling.
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Cross-Species Capability: Human, model organisms, non-model species, microbial communities, and environmental samples supported.
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Publication & IP Ready: Methods can be validated for use in publications, patents, or product commercialization.
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Advanced Bioinformatics: Custom pipelines built to analyze data from non-standard assays.
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Empowering Breakthroughs: We enable the science that others consider too complex, too risky, or too new.
What Is It Used For?
Our method development service has supported pioneering research in areas where existing technologies fall short. Examples include:
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Novel Epigenetic Marks: Designing assays to detect rare modifications (e.g., 5fC, 5caC) beyond standard methylation profiling.
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Hybrid Omics Workflows: Integrating sequencing with proteomics, metabolomics, or imaging-based analyses.
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Ultra-Low Input & Degraded Samples: Creating protocols for cfDNA, cfRNA, and FFPE samples that challenge standard workflows.
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Modified RNA Sequencing: Developing approaches for RNA modifications and chemical labeling strategies.
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Custom Panels for Rare Targets: Designing targeted panels for species-specific or disease-specific research.
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Proof-of-Concept Technologies: Building and testing new sequencing strategies for breakthrough research or commercialization.
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Complex Sample Types: Developing workflows for environmental, clinical, or industrial samples that standard methods cannot handle.
Frequently Asked Questions (FAQs)
Q: What makes AUGenomics different from other service providers?
A: While many labs offer fixed assays, AUGenomics is built for innovation. We collaborate directly with researchers to create entirely new methods, supporting high-risk, high-reward science.
Q: Do I need to provide a detailed protocol to start?
A: No. Share your research goals, challenges, and any existing references. We will co-develop the protocol with you.
Q: Can these methods be used for publication or commercialization?
A: Yes. Our development workflows can be validated for publication-ready and IP-generating results.
Q: What sample types can you work with?
A: Virtually any. We specialize in challenging and unconventional samples—from cfDNA to environmental matrices.
Q: How long does method development take?
A: Timelines vary based on complexity. Most projects have iterative phases and we work with you to define milestones and deliverables.
Why Choose AUGenomics?
Scientific Precision – Reliable data with high depth and accuracy
Custom Flexibility – Tailored protocols to match your research goals
Fast Turnaround – Streamlined workflows with rapid results
Human Partnership – A responsive, collaborative team invested in your success
From early-stage discovery to clinical or translational research, we’re here to make your sequencing journey faster, easier, and more impactful.
Your Partner in Genomics
Some of the most important breakthroughs in genomics began as unconventional ideas. AUGenomics was founded to support researchers who refuse to accept the limits of current technology. If your project requires thinking beyond the kit, we are the partner who will help you make it happen.
Not sure which method is best for your study? Whether you’re comparing whole exome sequencing vs. whole genome sequencing, exploring environmental DNA analysis, or need help with library preparation, we’re happy to guide you through the options.
We believe the best genomics work comes from real partnership—and we’re always ready to talk through your goals, questions, and challenges.
