Cell + Gene Therapy

Next-generation sequencing (NGS) has ushered in a transformative era for cell and gene therapy by providing comprehensive insights into the molecular intricacies of therapeutic interventions. NGS technologies play a pivotal role in characterizing the genetic profile of both therapeutic cells and target tissues, ensuring precision in the design and implementation of cell and gene therapies. The ability to sequence entire genomes or specific genetic regions enables researchers and clinicians to identify potential genetic abnormalities, confirm the integration of therapeutic genes, and monitor the persistence of modified cells in patients over time. This deep genomic understanding contributes to the optimization of therapeutic strategies, enhances the safety profile of treatments, and facilitates the development of personalized approaches. Moreover, NGS has become instrumental in quality control processes, ensuring the consistency and reliability of cell and gene therapy products. The integration of NGS in this field has accelerated advancements, bringing us closer to realizing the full potential of these innovative therapeutic modalities for a diverse range of diseases.