Key Focus:
IMMUNOLOGY +
ANTIBODY
Decoding the Immune System with Next-Generation Genomics
The immune system is nature’s most sophisticated defense network—and one of the most powerful frontiers for modern medicine. Understanding its complexity requires precision, depth, and scalability that only genomics can provide.
At AUGenomics, we partner with researchers in immunology, antibody discovery, and immuno-oncology to profile immune repertoires, map clonal diversity, and uncover the molecular signatures that drive immune response. Through next-generation sequencing (NGS), single-cell analysis, and advanced bioinformatics, we help scientists accelerate therapeutic antibody discovery, vaccine design, and immune monitoring—transforming data into discovery.
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Map the full TCR/BCR repertoire across samples or time points
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Identify novel antibody sequences and somatic variants
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Measure immune diversity and clonal expansion post-vaccination or therapy
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Characterize cytokine and immune pathway gene expression
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Discover immune biomarkers for response or toxicity prediction
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Link receptor sequences to antigen specificity or function
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Support therapeutic antibody development and validation
Why Genomics is Transforming Immunology
Every immune response tells a genetic story. Genomic and transcriptomic sequencing reveal the architecture of that story at single-cell resolution—identifying the unique rearrangements, somatic mutations, and expression profiles that shape antibody specificity and immune function.
NGS and single-cell technologies now allow researchers to:
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Profile TCR and BCR repertoires to map immune diversity and clonality
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Discover novel antibodies by sequencing heavy/light chain pairs and somatic hypermutation patterns
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Characterize immune responses to infection, vaccination, or therapy
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Identify biomarkers of immune activation, tolerance, or exhaustion
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Track clonal evolution in cancer immunotherapy or autoimmune disease
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Link receptor sequences to functional phenotypes through single-cell multi-omic profiling
AUGenomics integrates high-resolution sequencing with machine learning and repertoire analytics, enabling you to decode immune complexity, detect rare clones, and accelerate discovery from sequence to structure.
Common Sample Types
We support a wide range of immune-related sample types:
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PBMCs / whole blood — for repertoire profiling and immune monitoring
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Isolated B cells / T cells / plasma cells — for antibody or TCR discovery
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Lymphoid tissues (spleen, lymph node, tonsil) — for clonal expansion studies
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Tumor-infiltrating lymphocytes (TILs) — for immuno-oncology research
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Serum / plasma cfRNA — for cytokine and immune transcriptome analysis
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Hybridoma or recombinant antibody cell lines — for antibody gene sequencing and validation
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Single cells (10x Genomics, BD Rhapsody, etc.) — for immune repertoire and transcriptome co-analysis
Tailored Solutions
AUGenomics provides comprehensive genomic solutions for immunology and antibody discovery projects across academic, biotech, and translational programs.
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Immune Repertoire Sequencing: High-resolution TCR/BCR sequencing for clonotype diversity, lineage tracking, and immune profiling.
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Single-Cell Immune Profiling: Simultaneous capture of gene expression and receptor sequence data at single-cell resolution.
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Antibody Discovery: Identify and characterize heavy and light chain pairs, somatic hypermutations, and affinity maturation.
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Vaccine Response Studies: Profile antibody and T-cell dynamics pre- and post-vaccination.
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Immuno-Oncology Research: Characterize tumor-infiltrating lymphocytes (TILs) and immune checkpoint gene expression.
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Autoimmunity & Inflammation: Analyze immune signatures driving chronic inflammation or autoantibody production.
Explore our key sequencing solutions for Immunology & Antibody Discovery:
TCR/BCR Sequencing · Single-Cell RNA-seq · Bulk RNA-seq · Immune Transcriptomics · V(D)J Sequencing · Antibody Validation Sequencing
Why Us?
At AUGenomics, we combine scientific rigor with creative problem-solving to help you push the boundaries of immune discovery.
We deliver:
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End-to-end immune repertoire and transcriptomic analysis
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Customized workflows for rare, low-input, or complex immune samples
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Rapid turnaround times—results in as little as 3–5 days for select assays
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Seamless multi-omic integration for transcriptome, receptor, and epigenetic data
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Collaborative project design with our immunology-focused sequencing team
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Transparent communication via real-time project tracking in our client portal
Whether you’re engineering antibodies, exploring vaccine response, or decoding immune memory, we provide the genomic depth and partnership to move your research forward faster.
Let’s Work Together
Get in touch so we can start working together.
